UV degradation of deoxyribonucleic acid

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UV degradation of deoxyribonucleic acid

The effects of UV synchrotron radiation on deoxyribonucleic acid (DNA) cast films have been systematically investigated by vacuum ultraviolet and infrared spectrophotometry as a function of irradiation time. Cast DNA films exposed at 140 nm (8.85 eV) for different irradiations times, revealed consistent changes in their VUV spectra which indicate a decrease of thymine groups and an increase of ...

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Phleomycin-stimulated degradation of deoxyribonucleic acid in Escherichia coli.

Phleomycin stimulates the degradation of DNA by energy-dependent endonuclease and exonuclease reactions in Escherichia coli rec(+) cells and in recB(-) and recC(-) cells that lack an adenosine triphosphate-dependent nuclease functioning in the repair of ultraviolet (UV) lesions. Exonuclease activity is blocked in T4 phage-infected cells. The endonuclease reaction produces 10(7)-dalton segments ...

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ژورنال

عنوان ژورنال: Polymer Degradation and Stability

سال: 2009

ISSN: 0141-3910

DOI: 10.1016/j.polymdegradstab.2009.09.013